Dysbiosis of the gut microbiota in disease
نویسندگان
چکیده
There is growing evidence that dysbiosis of the gut microbiota is associated with the pathogenesis of both intestinal and extra-intestinal disorders. Intestinal disorders include inflammatory bowel disease, irritable bowel syndrome (IBS), and coeliac disease, while extra-intestinal disorders include allergy, asthma, metabolic syndrome, cardiovascular disease, and obesity.
منابع مشابه
Relationship between gut microbiota and type 2 diabetes
Diabetes is the most common endocrine disease following the spread of metabolic diseases worldwide. Diabetes is also the fifth leading cause of death in the world. Patients with type 2 diabetes account for about 90% of people with diabetes. Studies over the past years have shown a significant association between intestinal microbiota, intestinal dysbiosis, and metabolic syndrome. Changes in the...
متن کاملCorrelation of gut microbiota composition with colon adenomatous polyps
Microbiota is a collection of microorganisms that live in the oral cavity, respiratory tract and intestine of multicellular organisms. Microbiota exerts numerous physiological and pathological effects on the organism in which it resides. Increasing attention has been directed to the host-microbiota interaction, which is highly relevant to the development of carcinogenesis. Changes in the compos...
متن کاملInteraction between Intestinal Microbiota and Serotonin Metabolism
Gut microbiota regulates the production of signaling molecules, such as serotonin or 5-Hydroxytryptamine: 5-HT in the host. Serotonin is a biogenic amine that acts as a neurotransmitter in the gut and brain. There is a perfect interaction between human gastrointestinal microbiota and the serotonin system. The gut microbiota plays an important role in the serotonin signaling pathways through the...
متن کاملThe Effect of Intestinal Microbiota Metabolites on HT29 Cell line by Using MTT Method in Patients with Colorectal Cancer
Background: Colorectal cancer is one of the most common malignant tumors, Human guts harbor abundant microbes that adjust many aspects of host physiology. Increasing studies show that gut microbiota plays a significant role in the incidence and expansion of CRC, as a result of virulence factors, bacterial metabolites, or inflammatory pathways. Materials and Methods: In this study, viability o...
متن کاملRole of Gut Microbiome in Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a complex endocrine disorder that affects 8-13% of women at reproductive age worldwide. This disorder is usually associated with menstrual disorders, infertility, obesity, and insulin resistance. The underlying cause of this syndrome is unknown, however in recent years, researchers have shown an association between intestinal microbiota alterations )dysbiosi...
متن کاملP177: The Human Microbiome and PTSD, the Mechanisms of Interaction-A Narrative Review
present therapeutic methods for PTSD are not efficient enough to reduce or disappear all the symptoms.several peripheral factors can affect developing and treating PTSD, such as human microbiota. There is a growing volume of evidence showing the effect of gut microbiota on brain and behaviour.PTSD is associated with an inflammatory state in blood, brain and cerebrospinal fluid.also, there is ev...
متن کامل